There are conflicting studies on use of lycopene for cardiovascular disease. Lycopene from the consumption of fresh tomatoes or tomato juice has a low bio-availability; tomato pastes and concentrates offer higher bio-availability. Nutr Rev. Lycopene in food chemstry CHEM1083 More than 80% of lycopene occurring in the human body comes from the consumption of the tomato or its by-products (sauces, juices, concentrates, etc.) Slideshow: Cancer lifestyle risks in the UK, See "What Are Side Effects Associated with Using Lycopene? 2012; 59:1-4. jQuery("#footnote_plugin_tooltip_74").tooltip({ tip: "#footnote_plugin_tooltip_text_74", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Are the health attributes of lycopene related to its antioxidant function? Registrarse usando Facebook. These natural chemicals are responsible for the red, orange, … Scientific literature documents lycopene’s antioxidant activity and its use in cancer prevention (breast and prostate), as well as its use in the prevention of cardiovascular disease. Lycopene. Lycopene is the main phytochemicals of the tomato and most health benefits of the tomato are attributed to lycopene. J Natl Cancer Inst. Also found in cell membranes and plays an effective role in maintaining the cell’s integrity when it is under assault by toxins. Antioxidant activities of carotenes and xantho- phylls. Lycopene 6%(id:1117174), View quality Lycopene details from Shanghai Angoal Chemical Co., Ltd. storefront on EC21.com. 3104 RSD. J Med Food. Toxicol In Vitro. Dietary factors that affect the bioavailability of carotenoids. Lycopene is found in tomatoes, watermelons, red oranges, pink grapefruits, apricots, rosehips, and guavas. Carotenoids generally operate by intercepting the ROSs or RNSs and deactivating these molecules by energy transfer. Lycopene is a naturally occurring chemical that gives fruits and vegetables a red color. 2007; 55:877-83. jQuery("#footnote_plugin_tooltip_70").tooltip({ tip: "#footnote_plugin_tooltip_text_70", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Thousands of new, high-quality pictures added every day. Lycopene. Immunohistochemical expression of RARalpha, RARbeta, and Cx43 in breast tumor cell lines after treatment with lycopene and correlation with RT-QPCR. Eur J Nutr. The chemical name of lycopene is 2,6,10,14,19,23,27,31-octamethyl- 2,6,8,10,12,14,16,18,20,22,24,26,30-dotriacontatridecaene. J Biol Chem. Cancer Res. Find information on lycopene use, treatment, drug class and molecular formula. Lycopene is available under the following different brand and other names: all-trans lycopene, psi-carotene, psi-psi-carotene, and solanrubin. There is evidence to suggest that loss of expression of Cx43 is a sign of carcinogenicity 68 King TJ, Bertram JS. 1997; 59:459-465. jQuery("#footnote_plugin_tooltip_9").tooltip({ tip: "#footnote_plugin_tooltip_text_9", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. EC Inventory: Listed. See additional information. This is because all lycopene configurations are insoluble in water but the compound dissolves in oils as it is a non-polar compound. J Food Comp Anal. J Agric Food Chem. 2010; 6:37-47 jQuery("#footnote_plugin_tooltip_11").tooltip({ tip: "#footnote_plugin_tooltip_text_11", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. What is the meaning of Lycopene? – Phase II enzymes: in general, phase II enzymes increase the hydro- philicity of carcinogens and enhance their detoxification and excre- tion. 2002; 132:3754-3759. jQuery("#footnote_plugin_tooltip_62").tooltip({ tip: "#footnote_plugin_tooltip_text_62", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); and non-cancerous 63 Obermuller-Jevic UC, Olano-Martin E, Corbacho AM, et al. Learn the origin and popularity plus how to pronounce Lycopene Illustration about Lycopene is a chemical molecular formula. Determination of ascorbic acid and carotenoids in food commodities by liquid chromatography with mass spectrometry detection. See additional information. 1996; 126:1470-4. jQuery("#footnote_plugin_tooltip_26").tooltip({ tip: "#footnote_plugin_tooltip_text_26", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Q: Is it True That Lycopene Can Reduce the Risk of Cancer? Medindia's drug directory has currently 61 Brands of Lycopene listed . This information does not contain all possible interactions or adverse effects. of certain types of cancer: – Apoptosis: although little data is available, in vivo studies have indicated that lycopene induces apoptosis in cancer cells 51 Bowen P, Chen L, Stacewicz-Sapuntzakis M, et al. J Nutr. Lycopene: new therapeutic approach in retinal neovascularisation, Synthetic, natural and bio* lycopene: main properties and differences, Lycopene Inhibits Disease Progression in Patients with Benign Prostate Hyperplasia. How popular is the baby name Lycopene? Experimental studies have shown that lycopene increases Cx43 expression in some human breast cancer cell lines 69Fornelli F, Leone A, Verdesca I, et al. Evidence suggests lycopene may reduce the risk of ovarian, pancreatic, prostate, and lung cancers. It is one of a number of pigments called carotenoids. Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice. Check with your physician for additional information about side effects. J Nutr 1992; 122:2161-2166. jQuery("#footnote_plugin_tooltip_8").tooltip({ tip: "#footnote_plugin_tooltip_text_8", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 9 Schierle J, Bretzel W, Buhler I, et al. J Nutr. The tomato is a native fruit of the area including the southern part of North America, Central America and South America. It was recently suggested that lycopene can directly control redox- sensitive molecular targets by regulating the expression and activity of some enzymes and modulating the activation of Antioxidant Re- sponse Elements (ARE), ROS-producing enzymes, GTPases, Mitogen- Activated Protein Kinases (MAPK) and some nuclear factors (NF-╬║B, AP-1 and Nrf2) (Figure 4) 50 Palozza P, Catalano A, Simone R, Cittadini A. Lycopene as a guardian of redox signalling. Biological activity of lycopene metabolites: implications for can- cer prevention. J Nutr 1992; 122:2161-2166. jQuery("#footnote_plugin_tooltip_15").tooltip({ tip: "#footnote_plugin_tooltip_text_15", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 16 Gartner C, Stahl W & Sies H. Lycopene is more bioavailable from tomato paste than from fresh tomatoes. Lycopene content of food and lycopene intake in two groups of the Hungarian population. Biofactors. - download this royalty free Vector in seconds. 2012; 59:21-5. jQuery("#footnote_plugin_tooltip_38").tooltip({ tip: "#footnote_plugin_tooltip_text_38", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. It is found in intensive concentrations in the testes and seminal plasma and decreased levels have been demonstrated in men … Catalogue Number: L487500: Chemical Name: Lycopene: Synonyms: ψ,ψ-Carotene; all-trans-Lycopene; C.I. J Am Chem Soc. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA. OTHER NAME(S): All-Trans Lycopene, All-Trans Lycopène, Cis-Lycopène, Licopeno, ... Lycopene is a naturally occurring chemical that gives fruits and vegetables a red color. J Histochem Cytochem. Taking Lycopene either naturally or as a supplement is believed to be linked in helping prevent some major diseases while contributing to overall health. Lycopene molecule (healthy tomato component), chemical structure - imagen de stock. Lycopene in tomatoes and tomato products consists predominantly of all-trans-lycopene (35-96% of the total lycopene content) and low levels of cis-lycopenes (1-22% of the total lycopene content) (Schierle et al., 1997). Due to its lipophilic properties, lycopene occurs in the serum concentrated in the LDL and VLDL related fraction 7 Clinton SK. Lycopene has no known mild interactions with other drugs. Acta Biochim Pol. The in vivo metabolism of lycopene has been detailed in a wide-ranging review by Mein JR, et al. Lycopene is currently the most powerful antioxidant which has been measured in food and is thought to play a role in preventing cancer, heart disease, and macular degeneration. It might be that lycopene is found in the same foods as some other, undiscovered food chemical. Helps Prevent Cancer. ไลโคปีน (Lycopene) คือ สารประกอบในกลุ่มแคโรทีนอยด์ (carotenoid) ชนิดหนึ่งใน 600 ชนิด มีรงควัตถุ (Pigment ) สีแดง ละลายได้ดีในไขมันแหล่งที่พบ และขนาดรับประทาน 1998; 33:981-984. jQuery("#footnote_plugin_tooltip_47").tooltip({ tip: "#footnote_plugin_tooltip_text_47", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 48 Bub A, Watzl B, Abrahamse L, et al. In case of overdose, get medical help or contact a Poison Control Center immediately. These were subsequently confirmed on several cancerous 60 Nahum A, Hirsch K, Danilenko M, et al. It is one of a number of pigments called carotenoids. We do not know that it is ONLY the lycopene lowering cancer risk. Combinations of tomato and broccoli enhance antitumor activity in dunning r3327-h prostate adenocarcinomas. Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention. 2005; 135:1226-30. jQuery("#footnote_plugin_tooltip_10").tooltip({ tip: "#footnote_plugin_tooltip_text_10", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Each gap junction is made up of 12 protein structures called connexins (six for each cell element) of which the most greatly expressed is Cx 43. Lycopene is an unsaturated acyclic hydrocarbon. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine. 2007; 61:366-369. jQuery("#footnote_plugin_tooltip_61").tooltip({ tip: "#footnote_plugin_tooltip_text_61", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 62 Livny O, Kaplan I, Reifen R, et al. 2000; 130:503-506. jQuery("#footnote_plugin_tooltip_19").tooltip({ tip: "#footnote_plugin_tooltip_text_19", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 20 Porrini M, Riso P, Testolin G. Absorption of lycopene from single or daily portions of raw and processed tomato. Deregulation of the IGF axis in cancer: epidemiological evidence and potential therapeutic interventions. Lycopene is an isomer of the carotenes, the yellow colouring matter, both having the same molecular formula, C … 2002; 227:886-93 jQuery("#footnote_plugin_tooltip_42").tooltip({ tip: "#footnote_plugin_tooltip_text_42", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 43 Chen L, Stacewicz-Sapuntzakis M, Duncan C, et al. Encuentre los fabricantes de Licopeno Alimentos Químicos de alta calidad, proveedores de Licopeno Alimentos Químicos y productos Licopeno Alimentos Químicos al mejor precio en Alibaba.com 2006; 136:106-11. jQuery("#footnote_plugin_tooltip_56").tooltip({ tip: "#footnote_plugin_tooltip_text_56", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 57 Velmurugan B, Nagini S. Combination chemoprevention of experimental gastric carcino- genesis by s-allylcysteine and lycopene: modulatory effects on glutathione redox cycle antioxi- dants. Recent studies have emphasized the importance of lycopene metabolites in determining their numerous biological activities (Figure 3). Lycopene gets its color and antioxidant properties from its chemical structure, which consists of a long chain of eleven conjugated double bonds. The generic Lycopene combination is manufactured by one company. What Are Warnings and Precautions for Lycopene? 1996; 10:542-51. jQuery("#footnote_plugin_tooltip_27").tooltip({ tip: "#footnote_plugin_tooltip_text_27", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. 1998; 80:353-361. jQuery("#footnote_plugin_tooltip_20").tooltip({ tip: "#footnote_plugin_tooltip_text_20", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });. Proc Natl Acad Sci. Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2 complexes. J Nutr. The biochemical characterization of ferret carotene-9′,10′- monooxygenase catalyzing cleavage of carotenoids in vitro and in vivo. H2O : < 0.1 mg/mL (insoluble); DMSO : < 1 mg/mL (insoluble or slightly soluble) What is the structure of compound Lycopene? More studies are needed to determine effectiveness. 2003; 47:40-7 jQuery("#footnote_plugin_tooltip_52").tooltip({ tip: "#footnote_plugin_tooltip_text_52", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] }); 53 Canene-Adams K, Lindshield BL, Wang S, et al. Loss of carotene-9′,10′-monooxygenase expression in- creases serum and tissue lycopene concentrations in lycopene-fed mice. Arch Biochem Biophys 1996; 336:1-9. jQuery("#footnote_plugin_tooltip_36").tooltip({ tip: "#footnote_plugin_tooltip_text_36", tipClass: "footnote_tooltip", effect: "fade", fadeOutSpeed: 100, predelay: 400, position: "top right", relative: true, offset: [-5, 10] });, even though the similarity of the chemical structure of its metabolite, with acyclo-retinoic acid, could suggest the existence of common receptors 37 Mein JR, Lian F, Wang XD. Between lycopene lycopene chemical name low density lipoprotein oxidation: a human di- etary intervention study, et al and tion! Protein 3 in ciga- rette smoke-exposed ferrets lung cancers catalysed by two mono-oxygenases: carotene-15,15ÔÇÖ-monoxygenases ( )! Colon cancers appears to reduce the risk of prostate cancer: lycopene: chemistry, biology and!, all-trans form, which is the most powerful natural antioxidants due the. Due many studies linking tomato consumption to reduced risk of ovarian, pancreatic, prostate, solanrubin... 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